Pigmented progressive purpuric dermatosis - Dermatosis Purpura Progresif Berpigmen
https://en.wikipedia.org/wiki/Pigmented_purpuric_dermatosis
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Schamberg disease ― seorang pria berusia 26 tahun dengan bercak pigmentasi asimtomatik dan telangiektasia di kaki.
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References
Pigmented Purpuric Dermatoses: A Complete Narrative Review 34070260 NIH
Pigmented purpuric dermatoses (PPD) adalah sekelompok kondisi kulit yang ditandai dengan area kecil pendarahan di bawah kulit akibat peradangan kapiler. PPD biasanya dimulai dengan bintik merah hingga ungu yang kemudian berubah menjadi coklat keemasan saat hemosiderin diserap kembali.
Pigmented purpuric dermatoses (PPD) include several skin diseases characterized by multiple petechial hemorrhage as consequence of capillaritis. PPD generally present with red to purple macules that progressively evolve to golden-brown color as the hemosiderin is reabsorbed.
Schamberg Disease 32809367 NIH
Schamberg disease adalah jenis pigmented purpuric dermatoses (PPDs) yang paling umum, yaitu kondisi kulit kronis yang ditandai dengan bintik-bintik kecil berwarna merah atau ungu, dan peningkatan warna kulit (bercak coklat, merah, atau kuning) . PPD diklasifikasikan menjadi lima jenis: Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura, and eczematoid-like purpura of Doucas and Kapetanakis. Schamberg disease (SD) juga dikenal sebagai progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressiva, and Schamberg's purpura. Penyakit ini terutama menyerang pria dan biasanya muncul di kaki bagian bawah, namun bisa juga terjadi di paha, bokong, batang tubuh, atau lengan.
Schamberg disease represents the most common type of pigmented purpuric dermatoses (PPDs), a chronic, benign, cutaneous eruptions characterized by petechiae, purpura, and increased skin pigmentation (brown, red, or yellow patchy). The PPDs are grouped into five clinical entities: Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura and, eczematoid-like purpura of Doucas and Kapetanakis. Schamber disease (SD) has also been called: progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressive and, Schamberg's purpura. It is commonly seen in males and mainly affects the tibial regions, and could involve thighs, buttocks, trunk, or upper extremities.
Characteristics and Clinical Manifestations of Pigmented Purpuric Dermatosis 26273156 NIH
Informasi mengenai 113 pasien PPD dianalisis, termasuk 38 pasien yang menjalani biopsi kulit untuk penelitian ini. Tipe klinis terbanyak adalah penyakit Schamberg (60,5%) . Kondisi lain selain PPD adalah hipertensi (15,8%) , diabetes (10,5%) , dan lain-lain. Riwayat pengobatan mengungkapkan statin (13,2%) , beta blocker (10,5%) , dan lain-lain. Faktor yang mungkin terkait dengan PPD termasuk infeksi saluran pernapasan atas yang baru terjadi (5,3%) , berdiri terlalu lama yang menyebabkan tekanan ortostatik tinggi (2,6%) , dan olahraga berat (2,6%) . Pengobatan diberikan kepada 36 pasien (94,7%) - oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy.
Information on 113 patients with PPD was analyzed, and 38 subjects with skin biopsy were included for this study. Schamberg's disease was the most frequent clinical type (60.5%). Concomitant diseases included hypertension (15.8%), diabetes (10.5%), and others. Associated medication histories included statins (13.2%), beta blockers (10.5%), and others. Possibly associated etiologic factors were recent upper respiratory infection (5.3%), high orthostatic pressure due to prolonged standing (2.6%), and strenuous exercise (2.6%). A total of 36 patients (94.7%) were treated with one or more treatment methods, including oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy.
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